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Position: Home > issue > May 28, 2021 Volume 2, Issue 2
Genomic Variation, Origin Tracing and Vaccine Development of SARS-CoV-2: A Systematic Review
Category: Review
Author: Tianbao Li, Tao Huang, Cheng Guo, Ailan Wang, Xiaoli Shi, Xiaofei Mo, Qingqing Lu, Jing Sun, Tingting Hui, Geng Tian, Leyi Wang, Jialiang Yang

2.jpg

Graphical abstract


COVID-19 has spread globally to over 200 countries with more than 40 million confirmed cases and one million deaths as of November 1, 2020. The SARS-CoV-2 virus, leading to COVID-19, shows extremely high rates of infectivity and replication, and can result in pneumonia, acute respiratory distress, or even mortality. SARS-CoV-2 has been found to be continue rapidly evolving, with several genomic variants emerging in different regions throughout the world. In addition, despite intensive study of the spike protein, its origin and molecular mechanisms in mediating host invasion are still only partially resolved.





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