|
 |
On the cover: On the cover: Vivid life is everywhere in this blue planet. In this cover, four seasons are illustrated with diverse lives that are the traces of entire ecosystem circle. What a natural harmony! From birth to death, each species has its own life cycle and innate mechanisms decoded and to be decoded by scientists. The destiny of life cycle can be revealed by genome within a cell as the core of living beings. The more scientific discoveries about the core, the higher possibilities to disclose the truth of life. For sustainable development of our planet, it is important to build up one co-existing ecosystem for all living things. |
|
|
Add comment (English only) |
|
|
|
|
|
Position: Home > issue > January 25, 2022 Volume 3, Issue 1 |
|
|
|
Genomic basis of evolutionary adaptation in a warm-blooded fish |
Category: Report Download: PDF Figure Endnote |
Author: Xin Wang, Meng Qu, Yali Liu, Ralf F. Schneider, Yue Song, Zelin Chen, Hao Zhang, Yanhong Zhang, Haiyan Yu, Suyu Zhang, Dongxu Li, Geng Qin, Shaobo Ma, Jia Zhong, Jianping Yin, Shuaishuai Liu, Guangyi Fan, Axel Meyer, Dazhi Wang, Qiang Lin |
|
|

Graphical abstract Few fishes have evolved elevated body temperatures compared with ambient temperatures, and only in opah (Lampris spp) is the entire body affected. To understand the molecular basis of endothermy, we analyzed the opah genome and identified 23 genes with convergent amino acid substitutions across fish, birds, and mammals, including slc8b1, which encodes the mitochondrial Na+/Ca2+ exchanger and is essential for heart function and metabolic heat production. Among endothermic fishes, 44 convergent genes with suggestive metabolic functions were identified, such as glrx3, encoding a crucial protein for hemoglobin maturation.

|
|
|
|