|On the cover: On the cover: Vivid life is everywhere in this blue planet. In this cover, four seasons are illustrated with diverse lives that are the traces of entire ecosystem circle. What a natural harmony! From birth to death, each species has its own life cycle and innate mechanisms decoded and to be decoded by scientists. The destiny of life cycle can be revealed by genome within a cell as the core of living beings. The more scientific discoveries about the core, the higher possibilities to disclose the truth of life. For sustainable development of our planet, it is important to build up one co-existing ecosystem for all living things.|
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|Position: Home > issue > January 25, 2022 Volume 3, Issue 1|
|Experimental mapping of short-wavelength phonons in proteins|
|Category: Report Download: PDF Figure Endnote|
|Author: Utsab R. Shrestha, Eugene Mamontov, Hugh M. O'Neill, Qiu Zhang, Alexander I. Kolesnikov, Xiangqiang Chu|
Phonons are quasi-particles, observed as lattice vibrations in periodic materials, that often dampen in the presence of structural perturbations. Nevertheless, phonon-like collective excitations exist in highly complex systems, such as proteins, although the origin of such collective motions has remained elusive. Here we present a picture of temperature and hydration dependence of collective excitations in green fluorescent protein (GFP) obtained by inelastic neutron scattering. Our results provide evidence that such excitations can be used as a measure of flexibility/softness and are possibly associated with the protein¡¯s activity.
Shrestha U., Mamontov E., O¡¯Neill H., et al. (2021). Experimental Mapping of Short-wavelength Phonons in Protein. The Innovation. 3(1),100199.