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Position: Home > issue > March 29, 2022 Volume 3, Issue 2
Chemically Modified DNA Nanostructures for Drug Delivery
Category:   Review   Download:  PDF  Figure  Endnote
Author: Yuang Wang, Xuehe Lu, Xiaohui Wu, Yan Li, Wantao Tang, Changping Yang, Jianbing Liu, Baoquan Ding

Graphical Abstract


Based on predictable, complementary base pairing, deoxyribonucleic acid (DNA) can be artificially pre-designed into versatile DNA nanostructures of well-defined shapes and sizes. With excellent 


addressability and biocompatibility, DNA nanostructures have been widely employed in biomedical research, such as bio-sensing, bio-imaging, and drug delivery. With the development of the chemical biology of nucleic acid, chemically modified nucleic acids are also gradually developed to construct multifunctional DNA nanostructures.





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