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Position: Home > issue > May 10, 2022 Volume 3, Issue 4
Circulating cell-free DNA for early detection of cancers
Category:   Review   Download:  PDF  Figure  Endnote
Author: Qiang Gao, Qiang Zeng, Zhijie Wang, Chengcheng Li, Yu Xu, Peng Cui, Xin Zhu, Huafei Lu, Guoqiang Wang, Shangli Cai, Jie Wang, Jia Fan

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Graphical abstract


Effective screening modalities are currently available for only a small subset of cancers, and they generally have suboptimal performance with complicated procedures. Therefore, there is an urgent need to develop simple, accurate, and non-invasive methods for early detection ofcancers. Genetic and epigenetic alterations in plasma circulating cell-free DNA (cfDNA) have shown the potential to revolutionize methods of early detection of cancers and facilitate subsequent diagnosis to improve survival of patients.





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