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| On the cover: Medicine is the practice of the diagnosis, treatment, and prevention of disease. With the advances in medical science, human beings are getting both longer life spans and higher quality of life. From herbs to molecular signatures, humankind is experiencing a transition from traditional medicine to personalized medicine: the right treatment to the right patient at the right time. However, it is not so easy to achieve this goal because the etiology of most diseases and disorders is still unclear. From description to association, numerous researchers are working together to decipher the mechanisms behind disease. To address such challenges, more and more global collaborations are badly needed to include experts from all disciplines: not just doctors, scientists and administration staff, but also engineers, technicians and marketing managers. Not limited to a fish-eye view, we humans should widen our vision and get more deep insights beyond the human community. That is the right way to assure sustainable healthcare for humanity. |
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| Position: Home > issue > May 10, 2022 Volume 3, Issue 3 |
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| Demetallation of organometallic and metal-mediated reactions |
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The use of stoichiometric organometallic reagents and stoichiometric metals formed the basis of vast majority of classical reactions for constructing carbon¨Ccarbon bonds. The indispensable requirement of stoichiometric metals for such reactions constitutes significant challenges in terms of resource sustainability, operational safety, and chemical-waste management. The recent developments in C¨CH functionalizations, hydrogenative alkene/alkyne addition to electrophiles, the hydrazone umpolung chemistry, and other emerging fields such as the electrosynthesis and photoredox chemistry provide potential solutions to overcome these inherent challenges.
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