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Position: Home > issue > September 13, 2022 Volume 3, Issue 5
Co-existence and co-infection of influenza A viruses and coronaviruses: Public health challenges
Category:   Review   Download:  PDF  Figure  Endnote
Author: Jing Yang, Yuhuan Gong, Chunge Zhang, Ju Sun, Gary Wong, Weifeng Shi, Wenjun Liu, George F. Gao, Yuhai Bi

42.jpg

Graphical abstract


Since the 20th century, humans have lived through five pandemics caused by influenza A viruses (IAVs) (H1N1/1918, H2N2/1957, H3N2/1968, and H1N1/2009) and the coronavirus (CoV) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). IAVs and CoVs both have broad host ranges and share multiple hosts. Virus co-circulation and even co-infections facilitate genetic reassortment among IAVs and recombination among CoVs, further altering virus evolution dynamics and generating novel variants with increased cross-species transmission risk.





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