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Position: Home > issue > November 08, 2022 Volume 3, Issue 6
Neural circuits underlying motor and non-motor defects of Parkinson' s disease
Category:   Commentary   Download:  PDF  Figure  Endnote
Author: Minqing Jiang

a4.jpg

PF circuits underlying motor and mood defects of PD


Parkinson' s disease (PD) is a neurodegenerative disorder that causes unintended and uncontrollable movements, such as tremors, rigidity, and difficulty with balance and coordination. Neuronal degeneration in the basal ganglia network has been suggested as a likely cause for some PD symptoms. More specifically, such degeneration would lead to an imbalance between the direct pathway (from striatum to substantia nigra) and the indirect pathway (from striatum to pallidum), which subsequently drives movement deficits.





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