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Position: Home > issue > May 15, 2023 Volume 4, Issue 3
Etoposide, dexamethasone, and pegaspargase with sandwiched radiotherapy in early-stage natural killer/T-cell lymphoma: A randomized phase III study
Category:   Article   Download:  PDF  Figure  Endnote
Author: Huijuan Zhong,Shu Cheng,Xi Zhang,Bing Xu,Jiayi Chen,Xufeng Jiang,Jie Xiong,Yu Hu,Guohui Cui,Juying Wei,Wenbin Qian,Xiaobing Huang,Ming Hou,Feng Yan,Xin Wang,Yongping Song,Jianda Hu,Yuanhua Liu,Xuejun Ma,Fei Li,Chongyang Wu,Junmin Chen et al.

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GRAPHICAL ABSTRACT


Methotrexate, etoposide, dexamethasone, and pegaspargase (MESA) with sandwiched radiotherapy is known to be effective for early-stage extranodal natural killer/T-cell lymphoma, nasal type (NKTCL). We explored the efficacy and safety of reduced-intensity, non-intravenous etoposide, dexamethasone, and pegaspargase (ESA) with sandwiched radiotherapy. This multicenter, randomized, phase III trial enrolled patients aged between 14 and 70 years with newly diagnosed early-stage nasal NKTCL from 27 centers in China.





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