Revolutionizing genetic disease treatment: The case of exagamglogene autotemcel

Shuquan Rao; Yao Yao; Wenxuan Huo; Yang Cao; Lihua E. Budde

doi:10.1016/j.xinn.2024.100619

The Innovation > 2024 Vol. 5 > No. 3

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Revolutionizing genetic disease treatment: The case of exagamglogene autotemcel

1.
State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China
2.
Peking University People's Hospital, Peking University Institute of Hematology, National Clinical Research Center for Hematologic Disease, Beijing 100044, China
3.
Research Unit of Key Technique for Diagnosis and Treatments of Hematologic Malignancies, Chinese Academy of Medical Sciences (2019RU029), Beijing 100044, China
4.
Department of Hematology & Cancer Biology Research Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
5.
Department of Hematology & Hematopoietic Stem Cell Transplantation, City of Hope National Medical Center, Duarte, CA 91010, USA

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⁶These authors contributed equally
Corresponding authors: raoshuquan@ihcams.ac.cn (S.R); ebudde@coh.org (L.E.B.)
Received Date: 29 January 2024

Accepted Date: 27 March 2024

Published Online: 30 March 2024

The Innovation 5(3), https://doi.org/10.1016/j.xinn.2024.100619 | Cite this article

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REFERENCES

[1]	Kato, G.J., Piel, F.B., Reid, C.D., et al. (2018). Sickle cell disease. Nat. Rev. Dis. Primers 4: 18010. https://doi.org/10.1038/nrdp.2018.10. View in Article CrossRef Google Scholar
[2]	Origa, R. (2017). β-Thalassemia. Genet. Med. 19: 609-619. https://doi.org/10.1038/gim.2016.173. View in Article CrossRef Google Scholar
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[4]	(2023). FDA Approves First Gene Therapies to Treat Patients with Sickle Cell Disease. (FDA News release). https://www.fda.gov/news-events/press-announcements/fda-approves-first-gene-therapies-treat-patients-sickle-cell-disease. View in Article Google Scholar
[5]	(2024). CASGEVY (exagamglogene autotemcel) suspension for intravenous infusion. https://pi.vrtx.com/files/uspi_exagamglogene_autotemcel.pdf. View in Article Google Scholar

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Rao S., Yao Y., Huo W., et al., (2024). Revolutionizing genetic disease treatment: The case of exagamglogene autotemcel. The Innovation 5(3), 100619. https://doi.org/10.1016/j.xinn.2024.100619

Rao S., Yao Y., Huo W., et al., (2024). Revolutionizing genetic disease treatment: The case of exagamglogene autotemcel. The Innovation 5(3), 100619. https://doi.org/10.1016/j.xinn.2024.100619

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