The Innovation Life > 2023 Vol. 1 > No. 3 > 100041
Next Article Previous Article
COMMENTARY   Open Access     Cite

Next-generation liquid biopsy elucidates cfDNA origins from organ delineation to cellular population granularity

  • 1.

    Geneplus-Beijing, Beijing 102206, China

  • 2.

    Key Laboratory of Biomechanics and Mechanobiology, Ministry of Education, School of Engineering Medicine, Beihang University, Beijing 100191, China

  • 3.

    National Clinical Research Center for Cardiovascular Diseases, National Center for Cardiovascular Diseases, Beijing 100037, China

  • 4.

    Department of Rheumatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China

  • 5.

    Department of Nephrology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China

  • 6.

    Department of Henan Genomic Hospital, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China

  • 7.

    Department of Medical Genetics; Computation and Informatics in Biology and Medicine, University of Wisconsin-Madison, Madison 53706, USA

    • Show all affliationsShow less
More Information
  • Corresponding author: yix@geneplus.org.cn
  • Received Date:  09 October 2023
    Accepted Date:  21 November 2023
    Published Online:  04 December 2023
The Innovation Life  1(3),  https://doi.org/10.59717/j.xinn-life.2023.100041  |  Cite this article
    • FullText(HTML)
  • 加载中
    • REFERENCES
  • [1] Loyfer, N., Magenheim, J., Peretz, A., et al. (2023). A DNA methylation atlas of normal human cell types. Nature 613 : 355−364. DOI: 10.1038/s41586-022-05580-6.

    View in Article Google Scholar

    [2] Mattox, A.K., Douville, C., Wang, Y., et al. (2023). The Origin of Highly Elevated cell-free DNA in healthy individuals and patients with pancreatic, colorectal, lung, or ovarian cancer. Cancer Discov. 13 : 2166−2179. DOI: 10.1158/2159-8290.CD-21-1252.

    View in Article Google Scholar

    [3] Brusca, S.B., Elinoff, J.M., Zou, Y., et al. (2022). Plasma cell-free DNA predicts survival and maps specific sources of injury in pulmonary arterial hypertension. Circulation. 146 : 1033−1045. DOI: 10.1161/CIRCULATIONAHA.121.056719.

    View in Article Google Scholar

    [4] Gaitsch, H., Franklin, R.J.M., and Reich, D.S. (2023). Cell-free DNA-based liquid biopsies in neurology. Brain 146 : 1758−1774. DOI: 10.1093/brain/awac438.

    View in Article Google Scholar

    [5] Magenheim, J., Rokach, A., Peretz, A., et al. (2022). Universal lung epithelium DNA methylation markers for detection of lung damage in liquid biopsies. Eur. Respir. J. 60 : 2103056. DOI: 10.1183/13993003.03056-2021.

    View in Article Google Scholar

    • CITED BY

  • Cite this article:

    Chen R., Bai J., Zhang D., et al., (2023). Next-generation liquid biopsy elucidates cfDNA origins from organ delineation to cellular population granularity. The Innovation Life 1(3), 100041. https://doi.org/10.59717/j.xinn-life.2023.100041
    Chen R., Bai J., Zhang D., et al., (2023). Next-generation liquid biopsy elucidates cfDNA origins from organ delineation to cellular population granularity. The Innovation Life 1(3), 100041. https://doi.org/10.59717/j.xinn-life.2023.100041

PDF
Figures(1)    

Share

  • Share the QR code with wechat scanning code to friends and circle of friends.

Article Metrics

Article views(3561) PDF downloads(1291) Cited by(0)

Relative Articles

Article Contents
ABOUT THIS ARTICLE

Catalog

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return

    {{newsColumn.name}}

    Journal links

    {{newsColumn.name}}

    Stay connected

    Copyright © Innovation Press