The application of ultrasound for skin and appendage regeneration: A comprehensive review
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GRAPHICAL ABSTRACT
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PUBLIC SUMMARY
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Ultrasound has important application prospects in skin regeneration.
Ultrasound can affect cell behaviors by increasing DNA synthesis and inhibiting TNG signaling pathway.
Ultrasound can promote skin regeneration by directly using or combining with ultrasound-responsive materials.
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ABSTRACT
Ultrasound, an exogenous physical stimulus, has important application prospects in the field of regenerative medicine, especially in skin regeneration, due to its safety, controllability, and deep penetration depth. This review examines the potential of ultrasound therapy in promoting skin regeneration by exploring its effects on skin cells, mechanisms of action in regeneration, and responsive materials. With its deep tissue penetration and excellent biocompatibility, ultrasound presents an attractive option for enhancing wound healing and skin regeneration. By discussing current challenges and future prospects, this review offers insights to guide the development of innovative ultrasound-based approaches for clinical wound treatment. -
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REFERENCES
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Yu B., Li Z., and Huang S. (2024). The application of ultrasound for skin and appendage regeneration: A comprehensive review. The Innovation Life 2(2): 100074. https://doi.org/10.59717/j.xinn-life.2024.100074
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Yu B., Li Z., and Huang S. (2024). The application of ultrasound for skin and appendage regeneration: A comprehensive review. The Innovation Life 2(2): 100074. https://doi.org/10.59717/j.xinn-life.2024.100074
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Figure 1.
Schematic diagram of skin regeneration promoted by ultrasound.
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Figure 2.
Application of ultrasound for skin regeneration.
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Figure 3.
Ultrasound-responsive materials promote wound healing
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Figure 4.
Microenvironmental factors involved in sweat gland regeneration140
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Figure 5.
The future prospects of ultrasound
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