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The Innovation Medicine > 2026 Vol. 4 > No. 2 > 100208
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The dark side of immunity: From a byproduct of V(D)J recombination to a promoter of leukemic relapse

  • 1.

    Shanghai institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200031, China

  • 2.

    Shanghai Institute of Hematology, State Key Laboratory of Medical Genomics, National Research Center for Translational Medicine at Shanghai, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China

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  • Corresponding author: lwang@sinh.ac.cn
  • Received Date:  October 12, 2025
    Accepted Date:  March 18, 2026
    Published Online:  March 19, 2026
The Innovation Medicine  4(2),  https://doi.org/10.59717/j.xinn-med.2026.100208  |  Cite this article
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  • [1] Gao Z., Scott J.N.F., Edwards M.P., et al. (2025). Excised DNA circles from V(D)J recombination promote relapsed leukaemia. Nature 645:774−783. DOI:10.1038/s41586-025-09372-6

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  • Cite this article:

    Li Z., Chang B., Wang Y., et al. (2026). The dark side of immunity: From a byproduct of V(D)J recombination to a promoter of leukemic relapse. The Innovation Medicine 4:100208. https://doi.org/10.59717/j.xinn-med.2026.100208
    Li Z., Chang B., Wang Y., et al. (2026). The dark side of immunity: From a byproduct of V(D)J recombination to a promoter of leukemic relapse. The Innovation Medicine 4:100208. https://doi.org/10.59717/j.xinn-med.2026.100208

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