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The Innovation Nutrition > 2026 Vol. 1 > No. 2 > 100018
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11-Oxygenated androgens: An underrecognized endocrine axis for precision nutrition research

  • 1.

    Department of Pharmacy, Peking University Third Hospital, Beijing 100191, China

  • 2.

    Therapeutic Drug Monitoring and Clinical Toxicology Center for Peking University, Beijing 100191, China

  • 3.

    Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China

  • 4.

    National Clinical Research Center for Obstetrics and Gynecology, Peking University Third Hospital, Beijing 100191, China

  • 5.

    These authors contributed equally

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The Innovation Nutrition  1(2),  https://doi.org/10.59717/j.xinn-nutri.2026.100018  |  Cite this article
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  • [1] Turcu A. F., Rege J., Auchus R.J., et al. (2020). 11-oxygenated androgens in health and disease. Nat. Rev. Endocrinol. 16:284−296. DOI:10.1038/s41574-020-0336-x

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    [2] Walzer D., Turcu A. F., Jha S., et al. (2022). Excess 11-oxygenated androgens in women with severe insulin resistance are mediated by adrenal insulin receptor signaling. J. Clin. Endocrinol. Metab. 107:2626−2635. DOI:10.1210/clinem/dgac365

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    [3] McDonnell T., Anthony A. V., Clarke G., et al. (2025). Hepatic metabolism of 11-oxygenated androgens in humans: An integrated in vivo and ex vivo approach. Eur. J. Endocrinol. 193:340−347. DOI:10.1093/ejendo/lvaf166

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    [4] Xu H., Zhang H., Yang R., et al. (2026). From testosterone to 11-oxygenated androgens: Integrating endocrine biology, nutrition, and systemic health across the lifespan. Innov. Nutri. 1:100004. DOI:10.59717/j.xinn-nutri.2026.100004

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    [5] O'Reilly M. W., Kempegowda P., Jenkinson C., et al. (2017). 11-oxygenated C19 steroids are the predominant androgens in polycystic ovary syndrome. J. Clin. Endocrinol. Metab. 102:840−848. DOI:10.1210/jc.2016-3285

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  • Cite this article:

    Zhang X., Xu H., Li J., et al. (2026). 11-Oxygenated androgens: An underrecognized endocrine axis for precision nutrition research. The Innovation Nutrition 1:100018. https://doi.org/10.59717/j.xinn-nutri.2026.100018
    Zhang X., Xu H., Li J., et al. (2026). 11-Oxygenated androgens: An underrecognized endocrine axis for precision nutrition research. The Innovation Nutrition 1:100018. https://doi.org/10.59717/j.xinn-nutri.2026.100018

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