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The Innovation Drug Discovery > 2026 Vol. 1 > No. 2 > 100025
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Clinical pharmacy management of emerging intra-articular drug delivery systems for knee osteoarthritis: A practical guideline

  • 1.

    Institute of Orthopedics, Department of Orthopedics, The Fourth Medical Center of PLA General Hospital, National Clinical Research Center for Orthopedics, Sports Medicine & Rehabilitation, Beijing 100089, China

  • 2.

    Department of Orthopedics, The Second Affiliated Hospital of Harbin Medical University, Harbin Medical University, Harbin 150086, China

  • 3.

    School of Medicine, Nankai University, Tianjin 300350, China

  • 4.

    Department of Clinical Nutrition, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing 100730, China

  • 5.

    Department of Rehabilitation, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200336, China

  • 6.

    Yuanshen Rehabilitation Institute, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China

  • 7.

    These authors contributed equally

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The Innovation Drug Discovery  1(2),  https://doi.org/10.59717/j.xinn-drugdisc.2026.100025  |  Cite this article
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    • REFERENCES
  • [1] Uson, J., Rodriguez-García, S. C., Castellanos-Moreira, R., et al. (2021). EULAR recommendations for intra-articular therapies. Ann Rheum Dis, 80:1299−1305. DOI:10.1136/annrheumdis-2021-220266

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    [2] Wen, J., Li, H., Dai, H., Hua, S., et al. (2023). Intra-articular nanoparticles based therapies for osteoarthritis and rheumatoid arthritis management. Mater Today Bio, 19:100597. DOI:10.1016/j.mtbio.2023.100597

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    [3] Chen, J., Deng, M., Wang, J., et al. (2025). Recent advances in injectable hydrogels for osteoarthritis treatments. Front Bioeng Biotechnol, 13:1644222. DOI:10.3389/fbioe.2025.1644222

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    [4] Welsh, J. A., Goberdhan, D. C. I., O'Driscoll, L., et al. (2024). Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches. J Extracell Vesicles, 13:e12404. DOI:10.1002/jev2.12404

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    [5] DeJulius, C. R., Walton, B. L., Colazo, J. M., et al. (2024). Engineering approaches for RNA-based and cell-based osteoarthritis therapies. Nat Rev Rheumatol, 20:81−100. DOI:10.1038/s41584-023-01067-4

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  • Cite this article:

    Liu J., Wang Z., Shen H., et al. (2026). Clinical pharmacy management of emerging intra-articular drug delivery systems for knee osteoarthritis: A practical guideline. The Innovation Drug Discovery 1:100025. https://doi.org/10.59717/j.xinn-drugdisc.2026.100025
    Liu J., Wang Z., Shen H., et al. (2026). Clinical pharmacy management of emerging intra-articular drug delivery systems for knee osteoarthritis: A practical guideline. The Innovation Drug Discovery 1:100025. https://doi.org/10.59717/j.xinn-drugdisc.2026.100025

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