Molecular and cellular basis of life cycle transition provides new insights into ecological adaptation in jellyfish

Yongxue Li; Saijun Peng; Yali Liu; Ke Sun; Longjun Wu; Zhangyi Yu; Kai He; Yuanqing Ma; Fanghan Wang; Pengzhen Xu; Junyu Li; Tingting Sun; Huiwen Zheng; Lijing Ye; Lei Wang; Wenjin Hao; Jianmin Zhao; Qiang Lin; Kai Chen; Zhijun Dong

doi:10.59717/j.xinn-geo.2024.100063

The Innovation Geoscience > 2024 Vol. 2 > No. 2 > 100063

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Molecular and cellular basis of life cycle transition provides new insights into ecological adaptation in jellyfish

1.
Muping Coastal Environment Research Station, Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences, Yantai 264003, China
2.
University of Chinese Academy of Sciences, Beijing 100049, China
3.
CAS Key Laboratory of Tropical Marine Bio-resources and Ecology, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China
4.
State Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming 650500, China
5.
Department of Ocean Science, The Hong Kong University of Science and Technology, Hong Kong SAR 999077, China
6.
College of Bio-Medicine and Health, Huazhong Agricultural University, Wuhan 430070, China
7.
Key Laboratory of Conservation and Application in Biodiversity of South China, School of Life Sciences, Guangzhou University, Guangzhou 510006, China
8.
Shandong Key Laboratory of Marine Ecological Restoration, Shandong Marine Resource and Environment Research Institute, Yantai 264006, China
9.
School of Life Sciences, Fudan University, Shanghai 200438, China
10.
School of Life Science, Nantong University, Nantong 226019, China
11.
These authors contributed equally

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Corresponding authors: zjdong@yic.ac.cn (Z.D.); chenk@lpbr.cn (K.C.); linqiang@scsio.ac.cn (Q.L.); jmzhao@yic.ac.cn (J.Z.)
Received Date: September 12, 2023

Accepted Date: March 20, 2024

Published Online: March 28, 2024

The Innovation Geoscience 2(2), https://doi.org/10.59717/j.xinn-geo.2024.100063 | Cite this article

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PUBLIC SUMMARY

PUBLIC SUMMARY
1. We present a single-cell atlas for the jellyfish Aurelia coerulea during the polyp-to-medusa transition.
  
  We characterise variations in neural and muscle cells and gene expression patterns during strobilation.
  
  HOX1 plays a pivotal role in regulating the formation of striated muscle cells in A. coerulea.
  
  This study provides valuable insights into the cell biology and ecological adaptation of jellyfish.

ABSTRACT

ABSTRACT

Jellyfish are renowned for their complex life cycles and important ecological and evolutionary position. The unique transition from the sessile polyp to motile medusa stages is a key process determining a switch in jellyfish behaviour and regulating the formation of jellyfish blooms. Here, we presented a comprehensive cell atlas spanning four successive life cycle stages during the polyp-to-medusa transition in the scyphozoan jellyfish Aurelia coerulea. Moreover, we characterised the variation in cell composition and gene expression patterns during the phase transition, especially in the neuromuscular system. We found several previously unreported cell types that potentially underpin the complex swimming behaviour of jellyfish. Furthermore, we discovered the pivotal role of HOX1 in modulating the genesis of striated muscles in A. coerulea. Collectively, this study provides valuable insights into the cellular and molecular mechanisms underlying the complex life cycle transition and helps to advance our understanding of ecological adaptation in jellyfish.
- single-cell transcriptomic atlas /
- neuromuscular system /
- life cycle transition /
- jellyfish bloom

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Li Y., Peng S., Liu Y., et al., (2024). Molecular and cellular basis of life cycle transition provides new insights into ecological adaptation in jellyfish. The Innovation Geoscience 2(2): 100063. https://doi.org/10.59717/j.xinn-geo.2024.100063

Li Y., Peng S., Liu Y., et al., (2024). Molecular and cellular basis of life cycle transition provides new insights into ecological adaptation in jellyfish. The Innovation Geoscience 2(2): 100063. https://doi.org/10.59717/j.xinn-geo.2024.100063

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