| [1] | Poewe, W., Seppi, K., Tanner, C.M., et al. (2017). Parkinson disease. Nat. Rev. Dis. Primers 3: 17013. https://doi.org/10.1038/nrdp.2017.13. |
| [2] | Chen, Y., Hong, Z., Wang, J., et al. (2023). Circuit-specific gene therapy reverses core symptoms in a primate Parkinson's disease model. Cell 186: 5394–5410.e18. https://doi.org/10.1016/j.cell.2023.10.004. |
| [3] | Kravitz, A.V., Freeze, B.S., Parker, P.R.L., et al. (2010). Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry. Nature 466: 622–626. https://doi.org/10.1038/nature09159. |
| [4] | Li, H., and Jin, X. (2023). Multiple dynamic interactions from basal ganglia direct and indirect pathways mediate action selection. Elife 12: RP87644. https://doi.org/10.7554/eLife.87644. |
| [5] | Hammond, C., Bergman, H., and Brown, P. (2007). Pathological synchronization in Parkinson's disease: networks, models and treatments. Trends Neurosci. 30: 357–364. https://doi.org/10.1016/j.tins.2007.05.004. |
| Xunyi Yan, Xin Jin. Shedding light on gene therapy of Parkinson's disease in non-human primates[J]. The Innovation, 2024, 5(2). https://doi.org/10.1016/j.xinn.2024.100581 |
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The development of a new circuit-based gene therapy for Parkinson's disease