Mass spectrometry imaging-based multi-modal technique: Next-generation of biochemical analysis strategy

Take a typical mouse fetus imaging for example to clarify the characteristics of MSI-based multi-modal technique

Using advanced molecular imaging techniques, we can acquire the primary disturbance of spatial and temporal information based on histological variations, which has the potential to differentiate the intra-/extraheterogeneity and to predict disease progression or metastasis status in biological systems. Most of the biological and chemical imaging techniques depend on “inherent properties” to visualize the target compounds and their interactions from different forms of samples, such as elemental bond information, the mass-to-charge ratio (m/z), molecular fragment, ion mobility, and functional groups.

DOI:
https://doi.org/10.1016/j.xinn.2021.100151

Citation:
Zhao C., Guo L., Dong J., Cai Z. (2021). Mass spectrometry imaging-based multi-modal technique: Next-generation of biochemical analysis strategy. The Innovation. 2(4),100151.