MPoxVR – A comprehensive genomic resource for monkeypox virus variants surveillance

Statistical distribution of monkeypox virus genome sequence and variation

Monkeypox is a viral zoonotic disease endemic in Central and West Africa. Since 1 January 2022, 3413 laboratory confirmed monkeypox cases and one death have been reported from 50 countries/territories in five WHO regions, 1310 new cases and eight new countries have been reported in the past week. Genomic epidemiology is vital to determine the similarity between viruses and suggest possible links between cases, origins of infection, and transmission dynamics when combined with epidemiological information. However, one of the priority evidence gaps relating to the monkeypox outbreak is genome sequencing and in-host variation analysis.