| [1] | Yang, J.H., Hayano, M., Griffin, P.T., et al. (2023). Loss of epigenetic information as a cause of mammalian aging. Cell 186 :305-326.e327. DOI: 10.1016/j.cell.2022.12.027. |
| [2] | Maya-Mendoza, A., Moudry, P., Merchut-Maya, J.M., et al. (2018). High speed of fork progression induces DNA replication stress and genomic instability. Nature 559: 279−284. DOI: 10.1038/s41586-018-0261-5. |
| [3] | Debes, C., Papadakis, A., Gronke, S., et al. (2023). Ageing-associated changes in transcriptional elongation influence longevity. Nature 616: 814−821. DOI: 10.1038/s41586-023-05922-y. |
| [4] | Xie, J., de Souza Alves, V., von der Haar, T., et al. (2019). Regulation of the elongation phase of protein synthesis enhances translation accuracy and modulates lifespan. Curr. Biol. 29 :737-749 e735. DOI: 10.1016/j.cub.2019.01.029. |
| [5] | Cheng, F., Ji, Q., Wang, L., et al. (2023). Reducing oxidative protein folding alleviates senescence by minimizing ER-to-nucleus H2O2 release. EMBO Rep. 24: e56439. DOI: 10.15252/embr.202256439. |
| Cheng F. and Wang L. (2024). Slowing down the central dogma rate for alleviating aging. The Innovation Life 2(1): 100049. https://doi.org/10.59717/j.xinn-life.2024.100049 |
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Slowing down the ticking of the ‘central dogma’ clock can alleviate aging