An emerging role beyond genetics: DNA methylation in horticultural quality shaping
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GRAPHICAL ABSTRACT
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PUBLIC SUMMARY
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DNA methylation of 5-methyl-cytosine is found important for horticultural quality in this starting decade.
Promoter methylation and spreading of transposable element methylation are important function patterns.
Ripening, coloration, flavor volatiles, and cold action are highly methylation-affected.
The locus-specific methylation editing has been preliminarily accomplished and is developing.
The methylation-editing-mediated horticultural improvement may help address food challenges.
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ABSTRACT
Horticultural products play an increasingly vital role in addressing the nutritional needs of the world’s expanding population, which has surpassed 8 billion. The global trend towards health-oriented diets has motivated consumers to seek high-quality natural horticultural food consumption. This highlights the pressing requirement for updated guidance and strategies for sustainable horticultural quality upgrading. Meanwhile, DNA methylation, an epigenetic modification having transcriptional-regulation potential, is emerging as a crucial quality dominator of horticultural food. In this current investigation, we integrate valuable methylation loci regulating quality traits in fruit and vegetable, elucidating the underlying mechanisms and emphasizing the impressive species-specificity. At this early stage, the most extensively studied aspects of DNA methylation include promoter methylation and transposable elements. Additionally, we delve into locus-specific methylation-editing techniques, whose achievable genetic-modification-free advantages are promising to alleviate consumer concerns regarding genetic-modification products. Overall, this review is devoted to providing insights into the sustainable development of horticultural produce and food quality design strategies in response to global food quality and security challenges. -
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REFERENCES
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Chen Y., Li D., Lang Z., et al., (2024). An emerging role beyond genetics: DNA methylation in horticultural quality shaping. The Innovation Life 2(1): 100050. https://doi.org/10.59717/j.xinn-life.2024.100050
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Chen Y., Li D., Lang Z., et al., (2024). An emerging role beyond genetics: DNA methylation in horticultural quality shaping. The Innovation Life 2(1): 100050. https://doi.org/10.59717/j.xinn-life.2024.100050
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Figure 1.
The visualization of 5-methyl-cytosine (5mC) location and its roles in multifaceted specific quality traits of horticultural food.
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Figure 2.
The brief scheme for dynamics of DNA methylation
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Figure 3.
Potential function patterns of DNA methylation in the horticultural food quality formation and variation
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Figure 4.
Current research patterns of 5mC DNA methylation in horticultural species
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Figure 5.
The 5mC methylation roles in the ripening process and related overall quality aspects
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Figure 6.
Mainstream systems available for locus-specific manipulation of DNA methylation/demethylation targeted to FQRGs for horticultural quality design and a case of color control in Chrysanthemum morifolium flowers
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Figure 7.
Current efforts, supporting needed, and expected development of next-generation epigenetic modification strategy based on 5mC DNA methylation editing.
