Advanced Search
Article Contents
ABOUT THIS ARTICLE
The Innovation Life > 2025 Vol. 3 > No. 1 > 100110
Next Article Previous Article
COMMENTARY   Open Access     Cite

Merlin condensates: A solid foundation for the Hippo signaling pathway

  • 1.

    Department of Human Anatomy and Histoembryology, School of Basic Medical Sciences and Huadong Hospital, Shanghai Medical College, Fudan University, Shanghai 200040, China

  • 2.

    Institute of Microsurgery on Extremities, Department of Orthopedic Surgery, Shanghai Sixth People's Hospital Affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai 200233, China

  • 3.

    Division of Endocrinology and Metabolism, Department of Medicine, University of California San Diego, San Diego 92093, USA

  • 4.

    The Center for Microbes, Development, and Health; Shanghai Institute of Immunity and Infection, Chinese Academy of Sciences, Shanghai 200031, China

  • 5.

    Department of Orthopaedic Surgery, School of Medicine, Johns Hopkins University, Baltimore 21205, USA

  • 6.

    These authors contributed equally

    • Show all affliationsShow less
More Information
  • Corresponding author: wangzuoyun@fudan.edu.cn
  • Received Date:  September 26, 2024
    Accepted Date:  November 27, 2024
    Published Online:  December 11, 2024
The Innovation Life  3(1),  https://doi.org/10.59717/j.xinn-life.2024.100110  |  Cite this article
    • FullText(HTML)
  • 加载中
    • REFERENCES
  • [1] Guo P., Li B., Dong W., et al. (2024) PI4P-mediated solid-like Merlin condensates orchestrate Hippo pathway regulation. Science 385 :eadf4478. DOI:10.1126/science.adf4478

    View in Article Google Scholar

    [2] Pan D. (2022) The unfolding of the Hippo signaling pathway. Dev. Biol. 487 :1-9. DOI:10.1016/j.ydbio.2022.04.001

    View in Article Google Scholar

    [3] Liu Q., Li J., Zhang W., et al. (2021) Glycogen accumulation and phase separation drives liver tumor initiation. Cell 184 :5559-5576.e19. DOI:10.1016/j.cell.2021.10.001

    View in Article Google Scholar

    [4] Yu F.X., Zhao B., Guan K.L. Hippo pathway in organ size control, tissue homeostasis, and cancer. Cell 163 :811-28. DOI: 10.1016/j.cell.2015.10.044

    View in Article Google Scholar

    [5] Hu X., Wu X., Berry K., et al. (2023) Nuclear condensates of YAP fusion proteins alter transcription to drive ependymoma tumourigenesis. Nat. Cell Biol. 25 :323-336. DOI:10.1038/s41556-022-01069-6

    View in Article Google Scholar

    • Cited by

  • Cite this article:

    Wang X., Suo J., Feng X., et al. (2025). Merlin condensates: A solid foundation for the Hippo signaling pathway. The Innovation Life 3:100110. https://doi.org/10.59717/j.xinn-life.2024.100110
    Wang X., Suo J., Feng X., et al. (2025). Merlin condensates: A solid foundation for the Hippo signaling pathway. The Innovation Life 3:100110. https://doi.org/10.59717/j.xinn-life.2024.100110

Welcome!

To request copyright permission to republish or share portions of our works, please visit Copyright Clearance Center's (CCC) Marketplace website at marketplace.copyright.com.

PDF
Figures(1)    

Share

  • Share the QR code with wechat scanning code to friends and circle of friends.

Article Metrics

Article views(3632) PDF downloads(2240)

Relative Articles

Cited by

Catalog

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return

    {{newsColumn.name}}

    {{newsColumn.name}}

    Stay connected

    {{newsColumn.name}}

    Website copyright © Innovation Press. Published articles are licensed under CC BY with copyright retained by the authors.