| [1] | Lindley S.R., Subbaiah K.C.V., Priyanka F., et al. (2024). Ribozyme-activated mRNA trans-ligation enables large gene delivery to treat muscular dystrophies. Science 386:762−767. DOI:10.1126/science.adp8179 |
| [2] | Liu Z.-X., Zhang S., Zhu H.-Z., et al. (2024). Hydrolytic endonucleolytic ribozyme (HYER) is programmable for sequence-specific DNA cleavage. Science 383:eadh4859. DOI:10.1126/science.adh4859 |
| [3] | Puttaraju M., DiPasquale J., Baker C.C., et al. (2001). Messenger RNA repair and restoration of protein function by spliceosome-mediated RNA trans-splicing. Mol. Ther.: J Am. Soc. Gene Ther. 4:105−14. DOI:10.1006/mthe.2001.0426 |
| [4] | Berger A, Lorain S, Joséphine C, et al. (2015). Repair of rhodopsin mRNA by spliceosome-mediated RNA trans -splicing: a new approach for autosomal dominant retinitis pigmentosa. Mol. Ther. 23:918−930. DOI:10.1038/mt.2015.11 |
| [5] | Nemudraia A, Nemudryi A and Wiedenheft B. (2024). Repair of CRISPR-guided RNA breaks enables site-specific RNA excision in human cells. Science 384:808−814. DOI:10.1126/science.adk5518 |
| Lu L., Yuan L. and Huang Y. (2025). Manipulating ribozyme enlightens large fragment delivery: Sunshine of RNA repair to gene editing. The Innovation Life 3:100140. https://doi.org/10.59717/j.xinn-life.2025.100140 |
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Involvement of RNA repair mechanism in gene editing.