| [1] | Xuan, L., Wang, Y., Huang, F., et al. (2020). Sorafenib maintenance in patients with FLT3-ITD acute myeloid leukaemia undergoing allogeneic haematopoietic stem-cell transplantation: an open-label, multicentre, randomised phase 3 trial. Lancet Oncol. 21: 1201−1212. DOI: 10.1016/S1470-2045(20)30455-1. |
| [2] | Stone, R.M., Mandrekar, S.J., Sanford, B.L., et al. (2017). Midostaurin plus chemotherapy for acute myeloid Leukemia with a FLT3 mutation. N. Engl. J. Med. 377: 454−464. DOI: 10.1056/NEJMoa1614359. |
| [3] | Erba, H.P., Montesinos, P., Kim, H.J., et al. (2023). Quizartinib plus chemotherapy in newly diagnosed patients with FLT3-internal-tandem-duplication-positive Acute Myeloid leukaemia (QuANTUM-First): A randomised, double-blind, placebo-controlled, phase 3 trial. Lancet 401: 1571−1583. DOI: 10.1016/S0140-6736(23)00464-6. |
| [4] | Dohner, H., Wei, A.H., Appelbaum, F.R., et al. (2022). Diagnosis and management of AML in adults: 2022 recommendations from an international expert panel on behalf of the ELN. Blood 140: 1345−1377. DOI: 10.1182/blood.2022016867. |
| [5] | Daver, N., Perl, A.E., Maly, J., et al. (2022). Venetoclax plus Gilteritinib for FLT3-mutated relapsed/refractory Acute Myeloid Leukemia. J. Clin. Oncol. 40: 4048−4059. |
| Cao Y., Zhang C., Cao L., et al., (2023). Quizartinib is a good option for AML patients with FLT3-ITD mutations. The Innovation Medicine 1(1), 100007. https://doi.org/10.59717/j.xinn-med.2023.100007 |
To request copyright permission to republish or share portions of our works, please visit Copyright Clearance Center's (CCC) Marketplace website at marketplace.copyright.com.
The proposed treatment paradigm for FLT3-ITD AML.