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The Innovation Medicine > 2023 Vol. 1 > No. 2 > 100029
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First clinical trial of chronic spinal cord injury treated with a single drug

  • 1.

    Department of Laboratory Medicine, Zhejiang Provincial Hospital of Chinese Medicine, Hangzhou 310006, China

  • 2.

    The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310006, China

  • 3.

    Department of Clinical Research Center, Hangzhou First People's Hospital, Hangzhou 310006, China

More Information
  • Corresponding author: wangying@hmc.edu.cn
  • Received Date:  August 24, 2023
    Accepted Date:  September 12, 2023
    Published Online:  September 13, 2023
The Innovation Medicine  1(2),  https://doi.org/10.59717/j.xinn-med.2023.100029  |  Cite this article
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    • REFERENCES
  • [1] Khorasanizadeh, M., Yousefifard, M., Eskian, M., et al. (2019). Neurological recovery following traumatic spinal cord injury: a systematic review and meta-analysis. J Neurosurg Spine 15: 1−17.

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    [2] Karsy, M., and Hawryluk, G. (2017). Pharmacologic Management of Acute Spinal Cord Injury. Neurosurg Clin N Am 28: 49−62. DOI: 10.1016/j.nec.2016.07.002.

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    [3] Maynard, G., Kannan, R., Liu, J., et al. (2023). Soluble Nogo-Receptor-Fc decoy (AXER-204) in patients with chronic cervical spinal cord injury in the USA: a first-in-human and randomised clinical trial. Lancet Neurol 22: 672−684. DOI: 10.1016/S1474-4422(23)00215-6.

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    [4] Erik, C., Martin, J.R., Brandon, G., et al. (2018). A First-in-Human, Phase I Study of Neural Stem Cell Transplantation for Chronic Spinal Cord Injury. Cell Stem Cell 22: 941−950.e946. DOI: 10.1016/j.stem.2018.05.014.

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    [5] Wang, X., Zhou, T., Maynard, G.D., et al. (2020). Nogo receptor decoy promotes recovery and corticospinal growth in non-human primate spinal cord injury. Brain. 143. ,1697-1713.

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  • Cite this article:

    Lu K. and Wang Y. (2023). First clinical trial of chronic spinal cord injury treated with a single drug. The Innovation Medicine 1(2), 100029. https://doi.org/10.59717/j.xinn-med.2023.100029
    Lu K. and Wang Y. (2023). First clinical trial of chronic spinal cord injury treated with a single drug. The Innovation Medicine 1(2), 100029. https://doi.org/10.59717/j.xinn-med.2023.100029

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