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The Innovation Medicine > 2024 Vol. 2 > No. 4 > 100096
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Effect of anti-diabetic drugs in primary prevention of cardiovascular disease in type 2 diabetes and prediabetes: A systematic review and meta-analysis of randomized trials

  • 1.

    Institute of Clinical Medicine, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China

  • 2.

    Nutritional Epidemiology Group, School of Food Science & Nutrition, University of Leeds, Leeds LS29JT, UK

  • 3.

    Department of Epidemiology, School of Public Health, Sun Yat-sen University, Guangzhou 510080, China

  • 4.

    Department of Epidemiology and Biostatistics, Clinical Big Data Research Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen 518107, China

  • 5.

    Division of Hematology and Oncology, Yale New Haven Hospital, Yale University School of Medicine, New Haven CT 06510, USA

  • 6.

    Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong 999077, China

  • 7.

    Department of Computational Biology and Medical Big Data, Shenzhen University of Advanced Technology, Shenzhen 518107, China

  • 8.

    Shenzhen Institute of Advanced Technology, the Chinese Academy of Sciences, Shenzhen 518055, China

  • 9.

    JC School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong 999077, China

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  • Corresponding authors: zyang@cuhk.edu.hk (Z.Y.);  jltang@siat.ac.cn (J.T.)
  • Received Date:  July 02, 2024
    Accepted Date:  September 27, 2024
    Published Online:  October 28, 2024
The Innovation Medicine  2(4),  https://doi.org/10.59717/j.xinn-med.2024.100096  |  Cite this article
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    • REFERENCES
  • [1] American Diabetes Association Professional Practice Committee. (2024). 9. Pharmacologic approaches to glycemic treatment: Standards of care in diabetes-2024. Diabetes Care 47 : S158-S178. DOI: 10.2337/dc24-S009.

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    [3] Blood Pressure Lowering Treatment Trialists’ Collaboration, Ying, A., Arima, H., et al. (2015). Effects of blood pressure lowering on cardiovascular risk according to baseline body-mass index: A meta-analysis of randomised trials. Lancet 385: 867−874. DOI: 10.1016/S0140-6736(14)61171-5.

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    [4] Boussageon, R., Bejan-Angoulvant, T., Saadatian-Elahi, M., et al. (2011). Effect of intensive glucose lowering treatment on all cause mortality, cardiovascular death, and microvascular events in type 2 diabetes: Meta-analysis of randomised controlled trials. BMJ 343: d4169. DOI: 10.1136/bmj.d4169.

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    [5] Rodriguez-Gutierrez, R., Gonzalez-Gonzalez, J.G., Zuñiga-Hernandez, J.A., et al. (2019). Benefits and harms of intensive glycemic control in patients with type 2 diabetes. BMJ 367: l5887. DOI: 10.1136/bmj.l5887.

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    [6] Lamanna, C., Monami, M., Marchionni, N., et al. (2011). Effect of metformin on cardiovascular events and mortality: A meta-analysis of randomized clinical trials. Diabetes Obes. Metab. 13: 221−228. DOI: 10.1111/j.1463-1326.2010.01349.x.

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    [7] Zhu, Y.-Y., Yang, Z.-Y., Li, P., et al. (2020). Comparing the incidence of major cardiovascular events and severe microvascular complications in patients with type 2 diabetes mellitus: A systematic review and meta-analysis. World Journal of Meta-Analysis 8: 400−410. DOI: 10.13105/wjma.v8.i5.400.

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  • Cite this article:

    Zhang Y., Threapleton D., Shi H., et al., (2024). Effect of anti-diabetic drugs in primary prevention of cardiovascular disease in type 2 diabetes and prediabetes: A systematic review and meta-analysis of randomized trials. The Innovation Medicine 2(4): 100096. https://doi.org/10.59717/j.xinn-med.2024.100096
    Zhang Y., Threapleton D., Shi H., et al., (2024). Effect of anti-diabetic drugs in primary prevention of cardiovascular disease in type 2 diabetes and prediabetes: A systematic review and meta-analysis of randomized trials. The Innovation Medicine 2(4): 100096. https://doi.org/10.59717/j.xinn-med.2024.100096

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