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The Innovation Medicine > 2025 Vol. 3 > No. 1 > 100108
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Glucose-responsive oral insulin: A leap toward high-efficiency and safe diabetes management

  • 1.

    Department of Orthopaedics, Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases, Shanghai Institute of Traumatology and Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China

  • 2.

    Department of Spine Surgery Renji Hospital, Shanghai Jiao Tong University School of Medicine, 160 Pujian Road, Shanghai 200127, China

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The Innovation Medicine  3(1),  https://doi.org/10.59717/j.xinn-med.2024.100108  |  Cite this article
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  • [1] Sun H., Saeedi P., Karuranga S., et al. (2022). IDF Diabetes Atlas: Global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045. Diabetes Res. Clin. Pract. 183:109119. DOI:10.1016/j.diabres.2021.109119

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    [2] Ji K., Wei X., Kahkoska A. R., et al. (2024). An orally administered glucose-responsive polymeric complex for high-efficiency and safe delivery of insulin in mice and pigs. Nat. Nanotechnol. 19:1880−1891. DOI:10.1038/s41565-024-01764-5

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    [3] Spoorthi Shetty S., Halagali P., Johnson, A. P., et al. (2023). Oral insulin delivery: Barriers, strategies, and formulation approaches: A comprehensive review. Int. J. Biol. Macromol. 242:125114. DOI:10.1016/j.ijbiomac.2023.125114

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    [4] Blair H. A. (2024). Insulin icodec: First approval. BioDrugs 38:717−724. DOI:10.1007/s40259-024-00670-5

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    [5] Harris, E. (2023). FDA greenlights automated insulin dosing system for type 1 diabetes. JAMA 329:2011. DOI:10.1001/jama.2023.9602

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  • Cite this article:

    Li S., Zheng D. and Ruan R. (2025). Glucose-responsive oral insulin: A leap toward high-efficiency and safe diabetes management. The Innovation Medicine 3:100108. https://doi.org/10.59717/j.xinn-med.2024.100108
    Li S., Zheng D. and Ruan R. (2025). Glucose-responsive oral insulin: A leap toward high-efficiency and safe diabetes management. The Innovation Medicine 3:100108. https://doi.org/10.59717/j.xinn-med.2024.100108

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