Can iron serve as oocyte quality indicator in endometriosis?
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ABSTRACT
Endometriosis (EMs) is a significant cause of female infertility, and recent attention has focused on the relationship between iron levels in follicular fluid (FF) and oocyte quality. This perspective summarizes the characteristics of altered FF iron content and oocyte quality in EMs-associated infertility patients, along with detection methods and correlative studies. Current research indicates that dysregulated iron levels in the FF of EMs patients may be associated with diminished oocyte quality. However, the clinical utilization of FF iron content as an evaluation indicator faces multiple challenges. Future investigations should prioritize elucidating the regulatory mechanisms of iron homeostasis in the FF of EMs patients, establishing standardized detection and evaluation protocols, and providing novel insights for assisted reproductive therapies in EMs-related infertility cases. -
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REFERENCES
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Ni Z., Li Y. and Yu C. (2025). Can iron serve as oocyte quality indicator in endometriosis? The Innovation Medicine 3:100130. https://doi.org/10.59717/j.xinn-med.2025.100130
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Ni Z., Li Y. and Yu C. (2025). Can iron serve as oocyte quality indicator in endometriosis? The Innovation Medicine 3:100130. https://doi.org/10.59717/j.xinn-med.2025.100130
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Figure 1.
Challenges in assessing iron levels in follicular fluid
