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The Innovation Medicine > 2025 Vol. 3 > No. 4 > 100156
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Environmental neurotoxicity revisited: Evaluating microplastics as a potential risk factor for autism spectrum disorder

  • 1.

    Institute of Environment and Health, South China Hospital, Medical School, Shenzhen University, Shenzhen 518116, China

  • 2.

    Institute of Chronic Disease Risks Assessment, School of Nursing and Health, Henan University, Kaifeng 475004, China

  • 3.

    Department of Pediatric, South China Hospital, Medical School, Shenzhen University, Shenzhen 518116, China

  • 4.

    Department of Pediatric Health Care, South China Hospital, Medical School, Shenzhen University, Shenzhen 518116, China

  • 5.

    Department of Environmental Toxicology, School of Public Health, Shandong Second Medical University, Weifang 261053, China

  • 6.

    Department of Gastroenterology, South China Hospital, Medical School, Shenzhen University, Shenzhen 518116, China

  • 7.

    College of Public Health, Zhengzhou University, Zhengzhou 450001, China

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  • Corresponding author: nanliu@szu.edu.cn
  • Received Date:  June 24, 2025
    Accepted Date:  August 29, 2025
    Published Online:  September 02, 2025
The Innovation Medicine  3(4),  https://doi.org/10.59717/j.xinn-med.2025.100156  |  Cite this article
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    • REFERENCES
  • [1] Hirota T. and King B. H. (2023). Autism spectrum disorder: A review. JAMA 329:157−168. DOI:10.1001/jama.2022.23661

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    [2] Symeonides C., Vacy K., Thomson S., et al. (2024). Male autism spectrum disorder is linked to brain aromatase disruption by prenatal BPA in multimodal investigations and 10HDA ameliorates the related mouse phenotype. Nat. Commun. 15:6367. DOI:10.1038/s41467-024-48897-8

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    [3] Wang L., Li S., Hao Y., et al. (2024). Exposure to polystyrene microplastics reduces sociality and brain oxytocin levels through the gut-brain axis in mice. Sci. Total Environ. 945:174026. DOI:10.1016/j.scitotenv.2024.174026

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    [4] Żebrowska P., Łaczmańska I. and Łaczmański Ł. (2021). Future directions in reducing gastrointestinal disorders in children with ASD using fecal microbiota transplantation. Front. Cell. Infect. Microbiol. 11:630052. DOI:10.3389/fcimb.2021.630052

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    [5] Genovese A. and Butler M. G. (2020). Clinical assessment, genetics, and treatment approaches in autism spectrum disorder (ASD). Int. J. Mol. Sci. 21:4726. DOI:10.3390/ijms21134726

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  • Cite this article:

    Li L., Yang J., Wang Y., et al. (2025). Environmental neurotoxicity revisited: Evaluating microplastics as a potential risk factor for autism spectrum disorder. The Innovation Medicine 3:100156. https://doi.org/10.59717/j.xinn-med.2025.100156
    Li L., Yang J., Wang Y., et al. (2025). Environmental neurotoxicity revisited: Evaluating microplastics as a potential risk factor for autism spectrum disorder. The Innovation Medicine 3:100156. https://doi.org/10.59717/j.xinn-med.2025.100156

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