| [1] | Homan K. A., Gupta N., Kroll K. T., et al. (2019). Flow-enhanced vascularization and maturation of kidney organoids in vitro. Nat. Methods 16:255−262. DOI:10.1038/s41592-019-0325-y |
| [2] | Abilez O. J., Yang H., Guan Y., et al. (2025). Gastruloids enable modeling of the earliest stages of human cardiac and hepatic vascularization. Science 388:eadu9375. DOI:10.1126/science.adu9375 |
| [3] | Stuart T. and Satija R. (2019). Integrative single-cell analysis. Nat. Rev. Genet. 20:257−272. DOI:10.1038/s41576-019-0093-7 |
| [4] | Ronaldson-Bouchard K., Ma S. P., Yeager K., et al. (2018). Advanced maturation of human cardiac tissue grown from pluripotent stem cells. Nature 556:239−243. DOI:10.1038/s41586-018-0016-3 |
| [5] | Galie P. A., Nguyen D. H., Choi C. K., et al. (2014). Fluid shear stress threshold regulates angiogenic sprouting. Proc. Natl. Acad. Sci. U. S. A. 111:7968−7973. DOI:10.1073/pnas.1310842111 |
| Zhao D. and Luo H. (2026). Gastruloids unlock pathways to perfusable heart and liver organoids. The Innovation Medicine 4:100176. https://doi.org/10.59717/j.xinn-med.2026.100176 |
To request copyright permission to republish or share portions of our works, please visit Copyright Clearance Center's (CCC) Marketplace website at marketplace.copyright.com.
Gastruloid-guided generation of vascularised heart and liver organoids from a triple-reporter human embryonic stem cell (hESC) line