| [1] | Fearon E.R. and Vogelstein B. (1990). A genetic model for colorectal tumorigenesis. Cell 61:759−767. DOI:10.1016/0092-8674(90)90186-I |
| [2] | Lourenço F.C., Sadien I.D., Wong K., et al. (2025). Decay of driver mutations shapes the landscape of intestinal transformation. Nature 649:729−738. DOI:10.1038/s41586-025-09762-w |
| [3] | Canon J., Rex K., Saiki A.Y., et al. (2019). The clinical KRAS(G12C) inhibitor AMG 510 drives anti-tumour immunity. Nature 575:217−223. DOI:10.1038/s41586-019-1694-1 |
| [4] | Maxwell M.B., Hom-Tedla M.S., Yi J., et al. (2024). ARID1A suppresses R-loop-mediated STING-type I interferon pathway activation of anti-tumor immunity. Cell 187:3390−3408.e19. DOI:10.1016/j.cell.2024.04.025 |
| [5] | Martincorena I., Roshan A., Gerstung M., et al. (2015). High burden and pervasive positive selection of somatic mutations in normal human skin. Science 348:880−886. DOI:10.1126/science.aaa6806 |
| Duan H., Wen Z., Lei J., et al. (2027). The ecological imperative: Context and timing shape the path to colorectal cancer. The Innovation Medicine 5:100271. https://doi.org/10.59717/j.xinn-med.2027.100271 |
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Ecological "priming" dictates the trajectory of intestinal transformation