Advanced Search
Article Contents
ABOUT THIS ARTICLE
The Innovation Nutrition > Online
COMMENTARY   Open Access     Cite

Beyond glucose: How early lifestyle intervention rewires the long-term trajectory of multimorbidity and healthy aging

  • 1.

    Department of Nutrition and Food Hygiene, Hubei Key Laboratory of Food Nutrition and Safety, Huazhong University of Science and Technology, Wuhan 430030, China

  • 2.

    Key Laboratory of Health Effects of Environmental Pollution, School of Public Health, Huazhong University of Science and Technology, Wuhan 430030, China

  • 3.

    Prevention Research Collaboration, Sydney School of Public Health, The University of Sydney, Sydney, New South Wales 2006, Australia

  • 4.

    Charles Perkins Centre, The University of Sydney, Sydney, New South Wales 2006, Australia

  • 5.

    Department of Geriatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

  • 6.

    Key Laboratory of Vascular Aging, Ministry of Education, Tongji Hospital, Huazhong University of Science and Technology, Wuhan 430030, China

    • Show all affliationsShow less
More Information
The Innovation Nutrition  https://doi.org/10.59717/j.xinn-nutri.2026.100032  |  Cite this article
    • FullText(HTML)
  • 加载中
    • REFERENCES
  • [1] Salive M.E., Tjaden A.H., Ames J.R., et al. (2026). Lifestyle and metformin interventions and risk of multimorbidity in adults with prediabetes. JAMA. Published online June 15, 2026. DOI:10.1001/jama.2026.8492

    View in Article CrossRef Google Scholar

    [2] Gong Q, Zhang P, Wang J, et al. (2019). Morbidity and mortality after lifestyle intervention for people with impaired glucose tolerance: 30-year results of the da qing diabetes prevention outcome study. Lancet Diabetes Endocrinol. 7:452−461. DOI:10.1016/S2213-8587(19)30093-2

    View in Article CrossRef Google Scholar

    [3] Kulkarni AS, Gubbi S, and Barzilai N. (2020). Benefits of metformin in attenuating the hallmarks of aging. Cell Metab. 32:15−30. DOI:10.1016/j.cmet.2020.04.001

    View in Article CrossRef Google Scholar

    [4] Kroemer G, Maier A.B., Cuervo A.M., et al. (2025). From geroscience to precision geromedicine: Understanding and managing aging. Cell 188:2043−2062. DOI:10.1016/j.cell.2025.03.011

    View in Article CrossRef Google Scholar

    [5] Lincoff A.M., Brown-Frandsen K, Colhoun H.M., et al. (2023). Semaglutide and cardiovascular outcomes in obesity without diabetes. N Engl J Med. 389:2221−2232. DOI:10.1056/NEJMoa2307563

    View in Article CrossRef Google Scholar

    • Cited by

  • Cite this article:

    Luo G., Ding D., Liu M., et al. (2026). Beyond glucose: How early lifestyle intervention rewires the long-term trajectory of multimorbidity and healthy aging. The Innovation Nutrition 1:100032. https://doi.org/10.59717/j.xinn-nutri.2026.100032
    Luo G., Ding D., Liu M., et al. (2026). Beyond glucose: How early lifestyle intervention rewires the long-term trajectory of multimorbidity and healthy aging. The Innovation Nutrition 1:100032. https://doi.org/10.59717/j.xinn-nutri.2026.100032

Welcome!

To request copyright permission to republish or share portions of our works, please visit Copyright Clearance Center's (CCC) Marketplace website at marketplace.copyright.com.

PDF
Figures(1)    

Share

  • Share the QR code with wechat scanning code to friends and circle of friends.

Article Metrics

Article views(538) PDF downloads(155)

Relative Articles

Cited by

Catalog

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return

    {{newsColumn.name}}

    {{newsColumn.name}}

    Stay connected

    {{newsColumn.name}}

    Published articles are licensed under CC BY with copyright retained by the authors.
    All contents on this site: Copyright © 2026 INNOVATION PRESS. All rights are reserved.