| [1] | Bautmans I., Knoop V., Amuthavalli T. J., et al. (2022). WHO working definition of vitality capacity for healthy longevity monitoring. Lancet Healthy Longev. 3:e789−e796. DOI:10.1016/s2666-7568(22)00200-8 |
| [2] | Sperber A. D., Freud T., Palsson O. S., et al. (2024). The aging gastrointestinal tract: Epidemiology and clinical significance of disorders of gut-brain interaction in the older general population. Aliment. Pharmacol. Ther. 60:446−456. DOI:10.1111/apt.18103 |
| [3] | Sato S., Sasabuchi Y., Okada A., et al. (2025). Association between self-reported difficulty in chewing or swallowing and frailty in older adults: A retrospective cohort study. Geroscience 47:3497−3505. DOI:10.1007/s11357-024-01325-7 |
| [4] | Meng X., Yang J., Tan C., et al. (2026). Prevalence and distribution characteristics of digestive system function decline in older adults aged 60 and above in China, 2023. Chin. J. Prev. Med. 60:53−62. DOI:10.3760/cma.j.cn112150-20250914-00887 |
| [5] | Ferrucci L., and Fabbri E. (2018). Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty. Nat. Rev. Cardiol. 15:505−522. DOI:10.1038/s41569-018-0064-2 |
| Li Y., Zhao A. and Wu J. (2026). Digestive function decline: A missing dimension of healthy ageing. The Innovation Nutrition 1:100023. https://doi.org/10.59717/j.xinn-nutri.2026.100023 |
To request copyright permission to republish or share portions of our works, please visit Copyright Clearance Center's (CCC) Marketplace website at marketplace.copyright.com.
Digestive function decline in ageing: Burden, clinical roadmap, policy recommendations and future outlook.