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The Innovation Medicine > 2026 Vol. 4 > No. 1 > 100192
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The impact of maternal circadian rhythm disruption on offspring

  • 1.

    Research Center for Environment and Female Reproductive Health, the Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen 518033, China

  • 2.

    Department of Obstetrics, The Eighth Affiliated Hospital, Sun Yat-sen University, Shenzhen 518033, China

  • 3.

    Department of Reproductive Medicine, Shenzhen Maternity and Child Healthcare Hospital, Women and Children's Medical Center, Southern Medical University, Shenzhen 518033, China

  • 4.

    Department of Assisted Reproduction, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200023, China

  • 5.

    These authors contributed equally

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The Innovation Medicine  4(1),  https://doi.org/10.59717/j.xinn-med.2026.100192  |  Cite this article
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  • [1] Patke A., Young M.W. and Axelrod S. (2020). Molecular mechanisms and physiological importance of circadian rhythms. Nat. Rev. Mol. Cell. Biol. 21:67−84. DOI:10.1038/s41580-019-0179-2

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    [2] Mendez N., Halabi D., Spichiger C., et al. (2016). Gestational chronodisruption impairs circadian physiology in rat male offspring, increasing the risk of chronic disease. Endocrinology 157:4654−4668. DOI:10.1210/en.2016-1282

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    [4] Cui Z., Xu H., Wu F., et al. (2024). Maternal circadian rhythm disruption affects neonatal inflammation via metabolic reprograming of myeloid cells. Nat. Metab. 6:899−913. DOI:10.1038/s42255-024-01021-y

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    [5] Yao N., Kinouchi K., Katoh M., et al. (2025). Maternal circadian rhythms during pregnancy dictate metabolic plasticity in offspring. Cell Metab. 37:395−412.e396. DOI:10.1016/j.cmet.2024.12.002

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  • Cite this article:

    Lin Y., Cheng W., Weng H., et al. (2026). The impact of maternal circadian rhythm disruption on offspring. The Innovation Medicine 4:100192. https://doi.org/10.59717/j.xinn-med.2026.100192
    Lin Y., Cheng W., Weng H., et al. (2026). The impact of maternal circadian rhythm disruption on offspring. The Innovation Medicine 4:100192. https://doi.org/10.59717/j.xinn-med.2026.100192

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